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Symbol
Name
ID
Map2k4
mitogen-activated protein kinase kinase 4
MGI:1346869
Phenotype annotations related to liver/biliary system
Darker colors indicate more annotations
Human Phenotypes
Hepatosplenomegaly
Extrahepatic cholestasis
Jaundice
Neoplasm of the liver
Disease(s) Associated with MAP2K4
pancreatic cancer

Mouse Phenotypes
dilated liver sinusoidal space
liver hemorrhage
increased hepatocyte apoptosis
abnormal liver bud morphology
abnormal liver development
decreased hepatocyte number
Availability Mouse Genotype
Map2k4tm1Lizon/Map2k4tm1Lizon
Map2k4tm1Pngr/Map2k4tm1Pngr

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory